Variation of lipopolysaccharide-induced acute lung injury in eight strains of mice
AS Alm, K Li, H Chen, D Wang, R Andersson… - Respiratory physiology & …, 2010 - Elsevier
Clinical and experimental evidence suggests that genetic variations may play an important
role in the development of acute lung injury (ALI). Lipopolysaccharide (LPS)-induced ALI
models has been widely applied for pathophysiological and pharmacological research. In
order to understand the variation of acute pulmonary reactions between mouse strains and
find the optimal strain for target-oriented study, the present study investigated the alterations
of acute lung hyperinflation, inflammation and injury in C57BL/6J, Balb/cJ, DBA/1J, CD-1 …
role in the development of acute lung injury (ALI). Lipopolysaccharide (LPS)-induced ALI
models has been widely applied for pathophysiological and pharmacological research. In
order to understand the variation of acute pulmonary reactions between mouse strains and
find the optimal strain for target-oriented study, the present study investigated the alterations
of acute lung hyperinflation, inflammation and injury in C57BL/6J, Balb/cJ, DBA/1J, CD-1 …
