[HTML][HTML] Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol …

CM Jenkins, DJ Mancuso, W Yan, HF Sims… - Journal of Biological …, 2004 - ASBMB
Genetic knockout of hormone-sensitive lipase in mice has implicated the presence of other
intracellular triacylglycerol (TAG) lipases mediating TAG hydrolysis in adipocytes. Despite
intense interest in these TAG lipases, their molecular identities thus far are largely unknown.
Sequence data base searches for proteins containing calcium-independent phospholipase
A 2 (iPLA 2) dual signature nucleotide ((G/A) XGXXG) and lipase (GXSXG) consensus
sequence motifs identified a novel subfamily of three putative iPLA 2/lipase family members …