[HTML][HTML] Lipoxin B4 promotes the resolution of allergic inflammation in the upper and lower airways of mice
L Karra, O Haworth, R Priluck, BD Levy… - Mucosal …, 2015 - Elsevier
Chronic mucosal inflammation is the hallmark of important and common airway diseases,
such as allergic rhinitis (AR) and asthma. Lipoxin A 4 (LXA 4) is an endogenous pro-
resolving mediator for mucosal inflammation that decreases allergic and asthmatic
responses. Lipoxin B 4 (LXB 4) is a structurally distinct member of the lipoxin family that
signals in a manner distinct from LXA 4. LXB 4 is generated by mucosal tissues, but its
actions in allergic inflammation are unknown. Here, we used murine models of AR and …
such as allergic rhinitis (AR) and asthma. Lipoxin A 4 (LXA 4) is an endogenous pro-
resolving mediator for mucosal inflammation that decreases allergic and asthmatic
responses. Lipoxin B 4 (LXB 4) is a structurally distinct member of the lipoxin family that
signals in a manner distinct from LXA 4. LXB 4 is generated by mucosal tissues, but its
actions in allergic inflammation are unknown. Here, we used murine models of AR and …