Regulated cell death is intrinsically associated with inflammatory liver disease and is pivotal
in governing outcomes of metabolic liver disease. Different types of cell death may coexist
as metabolic liver disease progresses to inflammation, fibrosis, and ultimately cirrhosis. In
addition to apoptosis, lytic forms of hepatocellular death, such as necroptosis, pyroptosis
and ferroptosis elicit strong inflammatory responses due to cell membrane permeabilisation
and release of cellular components, contributing to the recruitment of immune cells and …