Serum basic fibroblastic growth factor levels in children with infantile hemangioma

HG Tanyildiz, EC Unal, H Gokce, G Yavuz… - The Indian Journal of …, 2016 - Springer
HG Tanyildiz, EC Unal, H Gokce, G Yavuz, N Tacyildiz, H Dincaslan, C Gurman, Z Biyikli
The Indian Journal of Pediatrics, 2016Springer
Objectives To determine serum levels of basic fibroblastic growth factor (b-FGF) in
hemangioma patients under 2 y of age. Methods The study group consisted of 43 children
with infantile hemangioma and b-FGF levels were analyzed using ELISA. Results The serum
b-FGF levels were higher in hemangioma patients than in healthy control individuals (p
0.01). There were no differences between the lesion size, number of lesions, patient age
and serum b-FGF levels. Conclusions Thus, b-FGF is an important growth factor that plays a …
Objectives
To determine serum levels of basic fibroblastic growth factor (b-FGF) in hemangioma patients under 2 y of age.
Methods
The study group consisted of 43 children with infantile hemangioma and b-FGF levels were analyzed using ELISA.
Results
The serum b-FGF levels were higher in hemangioma patients than in healthy control individuals (p 0.01). There were no differences between the lesion size, number of lesions, patient age and serum b-FGF levels.
Conclusions
Thus, b-FGF is an important growth factor that plays a central role in hemangioma, but determining b-FGF serum levels was not helpful in distinguishing between patients who require treatment and those who do not.
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