The mechanism of the plasma cholesterol esterification reaction: plasma fatty acid transferase

JA Glomset - Biochimica et biophysica acta, 1962 - Elsevier
The mechanism of cholesterol esterification in plasma incubated at 37° has been further
studied. The decrease in free cholesterol during incubation is accompanied by an
approximately equimolar decrease in lecithin. The initial rate of the cholesterol esterification
reaction in vitro in the plasma of normal human subjects is about 110 μmoles/l plasma/h.
During incubation a large proportion of the fatty acids which become esterified to cholesterol
are unsaturated, resembling in distribution the fatty acids of the C-2 position of the plasma …