This review describes production and effects of reactive oxygen species (ROS) on airway
function. ROS are important in many physiological processes but can also have detrimental
effects on airway cells and tissues when produced in high quantities or during the absence
of sufficient amounts of anti-oxidants. Therefore, these mediators play a prominent role in the
pathogenesis of various inflammatory airway disorders, including asthma. Effects of ROS on
airway function in asthma have been studied with isolated airway cells and tissues and with …