Racial pigmentation and the cutaneous synthesis of vitamin D

LY Matsuoka, J Wortsman, JG Haddad… - Archives of …, 1991 - jamanetwork.com
• The varying epidermal melanin content that produces racial pigmentation determines the
number of photons that reach the lower (malpighian) cellular layers, where vitamin D 3
synthesis takes place. We investigated the effect of racial pigmentation on vitamin D 3
formation, stimulating the process with a fixed dose of UVB radiation (wavelengths, 290 to
320 nm). Vitamin D nutritional status was further assessed measuring serum 25-
hydroxyvitamin D and the most active serum metabolite, 1, 25-dihydroxyvitamin D …