Impact of race and ethnicity in the course and outcome of systemic lupus erythematosus

LA González, SMA Toloza… - Rheumatic Disease …, 2014 - rheumatic.theclinics.com
Ethnicity is a biological and a social construct, which includes ancestral genes and cultural,
geographic, and socioeconomic characteristics shared by populations. 1, 2 In contrast, race
refers to genetically homogeneous groups of people, which is hardly the case for the human
race. 3 The US population is heterogeneous even within its ethnic groups, as shown when
ancestry informative markers (AIMs, genetic markers differentially expressed in founding
populations) were examined in the LUMINA (Lupus in Minorities: Nature vs Nurture) study; …