[HTML][HTML] PSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and …

TM Moore, R Garg, C Johnson, MJ Coptcoat… - Journal of Biological …, 2000 - ASBMB
Degenerate polymerase chain reaction against conserved kinase catalytic subdomains
identified 15 tyrosine and serine-threonine kinases expressed in surgically removed
prostatic carcinoma tissues, including six receptor kinases (PDGFBR, IGF1-R, VEGFR2,
MET, RYK, and EPH-A1), six non-receptor kinases (ABL, JAK1, JAK2, TYK2, PLK-1, and
EMK), and three novel kinases. Several of these kinases are oncogenic, and may function in
the development of prostate cancer. One of the novel kinases is a new member of the sterile …