Complex regional pain syndrome (CRPS) is a painful condition affecting one or more
extremities of the body, marked by a wide variety of symptoms and signs that are often
difficult to manage because the pathophysiology is incompletely understood. Thus, diverse
treatments might be ineffective. A recent report revealed the presence of autoantibodies
against differentiated autonomic neurons in CRPS patients. However, it remained unclear
how the antibodies act in the development of CRPS. We therefore aimed to characterize …