[HTML][HTML] Ligand-activated PPARδ modulates the migration and invasion of melanoma cells by regulating Snail expression

SA Ham, T Yoo, JS Hwang, ES Kang… - American journal of …, 2014 - ncbi.nlm.nih.gov
SA Ham, T Yoo, JS Hwang, ES Kang, WJ Lee, KS Paek, C Park, JH Kim, JT Do, DS Lim…
American journal of cancer research, 2014ncbi.nlm.nih.gov
Peroxisome proliferator-activated receptor (PPAR) δ is implicated in the carcinogenesis of
several types of cancer. However, the therapeutic efficacy of PPARδ ligands against cancer
progression is unclear. Here, we showed that PPARδ modulates the migration and invasion
of melanoma cells by up-regulating Snail expression. Activation of PPARδ by
Abstract
Peroxisome proliferator-activated receptor (PPAR) δ is implicated in the carcinogenesis of several types of cancer. However, the therapeutic efficacy of PPARδ ligands against cancer progression is unclear. Here, we showed that PPARδ modulates the migration and invasion of melanoma cells by up-regulating Snail expression. Activation of PPARδ by
ncbi.nlm.nih.gov