Clinical risk factors for mortality in patients with neurofibromatosis 1: a cohort study of 378 patients

K Khosrotehrani, S Bastuji-Garin, J Zeller… - Archives of …, 2003 - jamanetwork.com
Objective To identify the main clinical features associated with mortality in patients with
neurofibromatosis 1. Design Cohort study. Setting Referral center for neurofibromatosis.
Patients Three hundred seventy-eight patients with neurofibromatosis 1 who had more than
1 year of follow-up in the center. Main Outcome Measures Mortality. Clinical features,
especially dermatological, were evaluated as potential factors associated with mortality.
Results Factors associated independently with mortality were the presence of subcutaneous …