Management of systemic sclerosis-related skin disease: a review of existing and experimental therapeutic approaches
ER Volkmann, DE Furst - Rheumatic Disease Clinics, 2015 - rheumatic.theclinics.com
Virtually all patients with systemic sclerosis (SSc) experience cutaneous sclerosis and
Raynaud's phenomenon (RP), although substantial variability in the presentation and
severity of these cutaneous manifestations exist. Moreover, many patients with SSc exhibit
varying degrees of additional and often disabling cutaneous manifestations, such as digital
ulcers (DU), cutaneous telangiectasias, calcinosis, and pigment changes. The inherent
heterogeneity in these cutaneous manifestations complicates strategies for improving …
Raynaud's phenomenon (RP), although substantial variability in the presentation and
severity of these cutaneous manifestations exist. Moreover, many patients with SSc exhibit
varying degrees of additional and often disabling cutaneous manifestations, such as digital
ulcers (DU), cutaneous telangiectasias, calcinosis, and pigment changes. The inherent
heterogeneity in these cutaneous manifestations complicates strategies for improving …