Overweight and obesity are predictors of progression in early autosomal dominant polycystic kidney disease

KL Nowak, Z You, B Gitomer… - Journal of the …, 2018 - journals.lww.com
The association of overweight/obesity with disease progression in patients with autosomal
dominant polycystic kidney disease (ADPKD) remains untested. We hypothesized that
overweight/obesity associates with faster progression in early-stage ADPKD. Overall, 441
nondiabetic participants with ADPKD and an eGFR> 60 ml/min per 1.73 m 2 who
participated in the Halt Progression of Polycystic Kidney Disease Study A were categorized
on the basis of body mass index (BMI; calculated using nonkidney and nonliver weight) as …