The colony-stimulating factors and cancer
D Metcalf - Cancer immunology research, 2013 - AACR
D Metcalf
Cancer immunology research, 2013•AACRThe colony-stimulating factors (CSF) are the master regulators of granulocyte and
macrophage populations. There are four different aspects of the connection between the
CSFs and cancer:(i) the CSFs can accelerate the regeneration of protective white cells
damaged by chemotherapy;(ii) the CSFs can mobilize stem cells to the peripheral blood in
convenient numbers for transplantation;(iii) the CSFs can enhance anticancer immune
responses; and (iv) the CSFs are potentially involved in the genesis of the myeloid …
macrophage populations. There are four different aspects of the connection between the
CSFs and cancer:(i) the CSFs can accelerate the regeneration of protective white cells
damaged by chemotherapy;(ii) the CSFs can mobilize stem cells to the peripheral blood in
convenient numbers for transplantation;(iii) the CSFs can enhance anticancer immune
responses; and (iv) the CSFs are potentially involved in the genesis of the myeloid …
Abstract
The colony-stimulating factors (CSF) are the master regulators of granulocyte and macrophage populations. There are four different aspects of the connection between the CSFs and cancer: (i) the CSFs can accelerate the regeneration of protective white cells damaged by chemotherapy; (ii) the CSFs can mobilize stem cells to the peripheral blood in convenient numbers for transplantation; (iii) the CSFs can enhance anticancer immune responses; and (iv) the CSFs are potentially involved in the genesis of the myeloid leukemias. Cancer Immunol Res; 1(6); 351–6. ©2013 AACR.
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