Effectiveness of alimemazine in controlling retching after Nissen fundoplication
B Antao, K Ooi, N Ade-Ajayi, B Stevens… - Journal of pediatric surgery, 2005 - Elsevier
BACKGROUND: Retching, an early component of the emetic reflex, is a common and
distressing symptom in children after Nissen fundoplication. Alimemazine (trimeprazine,
Vallergan; Castlemead, Herts, UK) is a phenothiazine derivative histamine1 antagonist,
which anecdotally relieves the retching symptoms. MATERIAL AND METHODS: A
prospective, double-blind, randomized, crossover, placebo-controlled study of 15
neurologically impaired children with retching after Nissen fundoplication over a period of 1 …
distressing symptom in children after Nissen fundoplication. Alimemazine (trimeprazine,
Vallergan; Castlemead, Herts, UK) is a phenothiazine derivative histamine1 antagonist,
which anecdotally relieves the retching symptoms. MATERIAL AND METHODS: A
prospective, double-blind, randomized, crossover, placebo-controlled study of 15
neurologically impaired children with retching after Nissen fundoplication over a period of 1 …