Physiological bone remodeling is a highly coordinated process responsible for bone
resorption and formation and is necessary to repair damaged bone and to maintain mineral
homeostasis. In addition to the traditional bone cells (osteoclasts, osteoblasts, and
osteocytes) that are necessary for bone remodeling, several immune cells have also been
implicated in bone disease. This minireview discusses physiological bone remodeling,
outlining the traditional bone biology dogma in light of emerging osteoimmunology data …