[HTML][HTML] Mammalian target of rapamycin (mTOR) signaling network in skeletal myogenesis
Y Ge, J Chen - Journal of Biological Chemistry, 2012 - ASBMB
Mammalian (or mechanistic) target of rapamycin (mTOR) regulates a wide range of cellular
and developmental processes by coordinating signaling responses to mitogens, nutrients,
and various stresses. Over the last decade, mTOR has emerged as a master regulator of
skeletal myogenesis, controlling multiple stages of the myofiber formation process. In this
minireview, we present an emerging view of the signaling network underlying mTOR
regulation of myogenesis, which contrasts with the well established mechanisms in the …
and developmental processes by coordinating signaling responses to mitogens, nutrients,
and various stresses. Over the last decade, mTOR has emerged as a master regulator of
skeletal myogenesis, controlling multiple stages of the myofiber formation process. In this
minireview, we present an emerging view of the signaling network underlying mTOR
regulation of myogenesis, which contrasts with the well established mechanisms in the …