T Allele of nonsense polymorphism (rs2039381, Gln71Stop) of interferon-ε is a risk factor for the development of intracerebral hemorrhage
SK Kim, HJ Park, JW Kim, JH Chung, SD Yoo… - Human immunology, 2014 - Elsevier
Interferons (IFNs) play key roles in various biologic responses including antiviral and
immune reactions. We evaluated one possible risk factor in nonsense polymorphism
(rs2039381, Gln71Stop) of interferon-ε (IFNE). We recruited stroke [119 ischemic stroke (IS)
and 145 intracerebral hemorrhage (ICH)] and control (401), respectively. The nonsense
SNP (rs2039381, Gln71Stop) of IFNE was selected. We identified individual genotype using
sequencing. SNPStats and SPSS 18.0 programs were used to analyze genetic data …
immune reactions. We evaluated one possible risk factor in nonsense polymorphism
(rs2039381, Gln71Stop) of interferon-ε (IFNE). We recruited stroke [119 ischemic stroke (IS)
and 145 intracerebral hemorrhage (ICH)] and control (401), respectively. The nonsense
SNP (rs2039381, Gln71Stop) of IFNE was selected. We identified individual genotype using
sequencing. SNPStats and SPSS 18.0 programs were used to analyze genetic data …