Blood pressure and not uraemia is the major determinant of arterial stiffness and endothelial dysfunction in patients with chronic kidney disease and minimal co …
P Lilitkarntakul, N Dhaun, V Melville, S Blackwell… - Atherosclerosis, 2011 - Elsevier
INTRODUCTION: Patients with chronic kidney disease (CKD) have increased risk of
cardiovascular disease to which co-morbidity and associated conventional risk factors
contribute. We hypothesised that arterial stiffness (AS) and endothelial dysfunction (ED), as
surrogates of cardiovascular risk, would worsen as renal function declined even in patients
without co-morbidity and that this would relate to emerging cardiovascular risk factors.
METHODS: Carotid–femoral pulse wave velocity (PWV), as a measure of AS, and flow …
cardiovascular disease to which co-morbidity and associated conventional risk factors
contribute. We hypothesised that arterial stiffness (AS) and endothelial dysfunction (ED), as
surrogates of cardiovascular risk, would worsen as renal function declined even in patients
without co-morbidity and that this would relate to emerging cardiovascular risk factors.
METHODS: Carotid–femoral pulse wave velocity (PWV), as a measure of AS, and flow …