Cytokines and NASH: a pilot study of the effects of lifestyle modification and vitamin E

M Kugelmas, DB Hill, B Vivian, L Marsano, CJ McClain - Hepatology, 2003 - Elsevier
There are few data evaluating plasma and/or peripheral blood monocyte cytokine
concentrations/production or attempts to manipulate proinflammatory cytokines in
nonalcoholic steatohepatitis (NASH). A pilot project in a general clinical research center
evaluated the effects of a step 1 American Heart Association diet plus aerobic exercise with
or without 800 IU of vitamin E daily on cytokine profiles and liver enzyme levels in 16
patients with biopsy-proven NASH. Biochemical assessment of liver function, lipid profiles …