Natural antisense mRNAs to hyaluronan synthase 2 inhibit hyaluronan biosynthesis and cell proliferation
H Chao, AP Spicer - Journal of Biological Chemistry, 2005 - ASBMB
We report the identification of a natural antisense mRNA of hyaluronan synthase 2 that we
have chosen to designate as HASNT (for HA synthase 2 antisense) in human and mouse.
HASNT is transcribed from the opposite strand of the HAS2 gene locus and is represented
by several independent expressed sequence tags in human. Portions of the mouse Hasnt
gene were identified through an exon-trapping approach. Sequence conservation is
extremely low between human and mouse HASNT, and it is not clear whether these mRNAs …
have chosen to designate as HASNT (for HA synthase 2 antisense) in human and mouse.
HASNT is transcribed from the opposite strand of the HAS2 gene locus and is represented
by several independent expressed sequence tags in human. Portions of the mouse Hasnt
gene were identified through an exon-trapping approach. Sequence conservation is
extremely low between human and mouse HASNT, and it is not clear whether these mRNAs …
