Decrease of platelet-endothelial cell adhesion molecule 1-gene-expression in inflammatory cells and in endothelial cells in the rat liver following CCl4-administration …
K Neubauer, A Ritzel, B Saile, G Ramadori - Immunology Letters, 2000 - Elsevier
Platelet-endothelial cell adhesion molecule (PECAM-1), a member of the Ig superfamily is
strongly expressed at endothelial cell–cell junctions, on most leukocytes and on monocytes.
PECAM-1 has been implicated as a key mediator of the transendothelial migration of
leukocytes and monocytes. To further define the physiological role of PECAM-1, we studied
the modulation of PECAM-1-expression in a model of liver inflammation in both
mononuclear cells (MCs) and sinusoidal endothelial cells (SECs). In normal rat liver …
strongly expressed at endothelial cell–cell junctions, on most leukocytes and on monocytes.
PECAM-1 has been implicated as a key mediator of the transendothelial migration of
leukocytes and monocytes. To further define the physiological role of PECAM-1, we studied
the modulation of PECAM-1-expression in a model of liver inflammation in both
mononuclear cells (MCs) and sinusoidal endothelial cells (SECs). In normal rat liver …