Glutathione peroxidase 3 serum levels and GPX3 gene polymorphisms in subjects with metabolic syndrome

BG Baez-Duarte, F Mendoza-Carrera… - Archives of Medical …, 2014 - Elsevier
Background and Aims Glutathione peroxidase 3 (GPx3) plays a main role in removing hydro-
and lipoperoxides from the body. Changes in concentration and several single-nucleotide
polymorphisms (SNP) at the GPX3 gene have been associated with vascular diseases, but
the relationship of GPx3 with metabolic syndrome (MetS) remains unexplored. We
undertook this study to determine the association of GPx3 serum levels and several GPX3
SNPs with the presence of MetS in Mexican subjects. Methods Clinical, biochemical, and …