CD57+ T lymphocytes and functional immune deficiency

D Focosi, M Bestagno, O Burrone… - Journal of leukocyte …, 2010 - Wiley Online Library
D Focosi, M Bestagno, O Burrone, M Petrini
Journal of leukocyte biology, 2010Wiley Online Library
CD57+ expression in T lymphocytes has been recognized for decades as a marker of in vitro
replicative senescence. In recent years, accumulating evidences have pointed on the utility
of this marker to measure functional immune deficiency in patients with autoimmune
disease, infectious diseases, and cancers. We review here the relevant literature and
implications in clinical settings.
CD57+ expression in T lymphocytes has been recognized for decades as a marker of in vitro replicative senescence. In recent years, accumulating evidences have pointed on the utility of this marker to measure functional immune deficiency in patients with autoimmune disease, infectious diseases, and cancers. We review here the relevant literature and implications in clinical settings.
Wiley Online Library