[PDF][PDF] Pilot study using molecular profiling of patients' tumors to find potential targets and select treatments for their refractory cancers

DD Von Hoff, JJ Stephenson Jr, P Rosen, DM Loesch… - J Clin Oncol, 2010 - academia.edu
DD Von Hoff, JJ Stephenson Jr, P Rosen, DM Loesch, MJ Borad, S Anthony, G Jameson…
J Clin Oncol, 2010academia.edu
Pilot Study Using Molecular Profiling of Patients’ Tumors to Find Potential Targets and Select
Treatments for Their Refractory Page 1 Pilot Study Using Molecular Profiling of Patients’
Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers Daniel D.
Von Hoff, Joseph J. Stephenson Jr, Peter Rosen, David M. Loesch, Mitesh J. Borad, Stephen
Anthony, Gayle Jameson, Susan Brown, Nina Cantafio, Donald A. Richards, Tom R. Fitch,
Ernesto Wasserman, Cristian Fernandez, Sylvan Green,† William Sutherland, Michael Bittner …
Purpose
To compare the progression-free survival (PFS) using a treatment regimen selected by molecular profiling (MP) of a patient’s tumor with the PFS for the most recent regimen on which the patient had experienced progression (ie, patient as his own control).
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