Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals
Objectives: To identify novel loci for late-onset Alzheimer disease (LOAD) in Caribbean
Hispanic individuals and to replicate the findings in a publicly available data set from the
National Institute on Aging Late-Onset Alzheimer's Disease Family Study. Design: Nested
case-control genome-wide association study. Setting: The Washington Heights–Inwood
Columbia Aging Project and the Estudio Familiar de Influencia Genetica de Alzheimer study.
Participants: Five hundred forty-nine affected and 544 unaffected individuals of Caribbean …
Hispanic individuals and to replicate the findings in a publicly available data set from the
National Institute on Aging Late-Onset Alzheimer's Disease Family Study. Design: Nested
case-control genome-wide association study. Setting: The Washington Heights–Inwood
Columbia Aging Project and the Estudio Familiar de Influencia Genetica de Alzheimer study.
Participants: Five hundred forty-nine affected and 544 unaffected individuals of Caribbean …
