Therapeutic insights from genomic studies of head and neck squamous cell carcinomas
PS Hammerman, DN Hayes, JR Grandis - Cancer discovery, 2015 - AACR
PS Hammerman, DN Hayes, JR Grandis
Cancer discovery, 2015•AACRLarge and comprehensive genomic surveys of head and neck squamous cell carcinomas
(HNSCC) are now greatly increasing our understanding of the diversity of this disease and
the key genomic changes that drive these tumors. The results from these studies are
beginning to inform the introduction of novel therapies for patients with HNSCCs. Here, we
review some of the key findings from recent genomic studies of head and neck cancers,
including the most comprehensive study to date from The Cancer Genome Atlas Network …
(HNSCC) are now greatly increasing our understanding of the diversity of this disease and
the key genomic changes that drive these tumors. The results from these studies are
beginning to inform the introduction of novel therapies for patients with HNSCCs. Here, we
review some of the key findings from recent genomic studies of head and neck cancers,
including the most comprehensive study to date from The Cancer Genome Atlas Network …
Abstract
Large and comprehensive genomic surveys of head and neck squamous cell carcinomas (HNSCC) are now greatly increasing our understanding of the diversity of this disease and the key genomic changes that drive these tumors. The results from these studies are beginning to inform the introduction of novel therapies for patients with HNSCCs. Here, we review some of the key findings from recent genomic studies of head and neck cancers, including the most comprehensive study to date from The Cancer Genome Atlas Network. Cancer Discov; 5(3); 239–44. ©2015 AACR.
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