Effector activity of OKT4+ and OKT8+ T-cell subsets in lectin-dependent cell-mediated cytotoxicity against adherent HEp-2 cells
A Perl, R Gonzalez-Cabello, I Láng, P Gergely - Cellular immunology, 1984 - Elsevier
The role of OKT4+ and OKT8+ T-cell subsets was studied in lectin-dependent cell-mediated
cytotoxicity (LDCC) against adherent HEp-2 human epipharynx carcinoma target cells.
LDCC was evaluated by detachment from the monolayer of [3 H] thymidine prelabeled HEp-
2 cells in a 24-hr assay with a concanavalin A (Con A) dose of 25 μg/ml at effectortarget cell
ratios of 5: 1, 25: 1, and 50: 1. Under these conditions but without Con A considerable
natural cell-mediated cytotoxicity (NCMC) was not elicited; however, the cytotoxicity was …
cytotoxicity (LDCC) against adherent HEp-2 human epipharynx carcinoma target cells.
LDCC was evaluated by detachment from the monolayer of [3 H] thymidine prelabeled HEp-
2 cells in a 24-hr assay with a concanavalin A (Con A) dose of 25 μg/ml at effectortarget cell
ratios of 5: 1, 25: 1, and 50: 1. Under these conditions but without Con A considerable
natural cell-mediated cytotoxicity (NCMC) was not elicited; however, the cytotoxicity was …