[HTML][HTML] Upstream stimulatory factors binding to an E box motif in the R region of the bovine leukemia virus long terminal repeat stimulates viral gene expression
C Calomme, TLA Nguyên, Y De Launoit… - Journal of Biological …, 2002 - ASBMB
The bovine leukemia virus (BLV) promoter is located in its 5′-long terminal repeat and is
composed of the U3, R, and U5 regions. BLV transcription is regulated bycis-acting
elements located in the U3 region, including three 21-bp enhancers required for
transactivation of the BLV promoter by the virus-encoded transactivator Tax BLV. In addition
to the U3 cis-acting elements, both the R and U5 regions contain stimulatory sequences. To
date, no transcription factor-binding site has been identified in the R region. Here sequence …
composed of the U3, R, and U5 regions. BLV transcription is regulated bycis-acting
elements located in the U3 region, including three 21-bp enhancers required for
transactivation of the BLV promoter by the virus-encoded transactivator Tax BLV. In addition
to the U3 cis-acting elements, both the R and U5 regions contain stimulatory sequences. To
date, no transcription factor-binding site has been identified in the R region. Here sequence …