Small and medium sized HDL particles are protectively associated with coronary calcification in a cross-sectional population-based sample
C Ditah, J Otvos, H Nassar, D Shaham, R Sinnreich… - Atherosclerosis, 2016 - Elsevier
Background and aims Failure of trials to observe benefits by elevating plasma high-density
lipoprotein cholesterol (HDL-C) has raised serious doubts about HDL-C's atheroprotective
properties. We aimed to identify protective HDL biomarkers by examining the association of
nuclear magnetic resonance (NMR) measures of total HDL-particle (HDL-P), large HDL-
particle, and small and medium-sized HDL-particle (MS-HDL-P) concentrations and average
HDL-particle size with coronary artery calcification (CAC), which reflects the burden of …
lipoprotein cholesterol (HDL-C) has raised serious doubts about HDL-C's atheroprotective
properties. We aimed to identify protective HDL biomarkers by examining the association of
nuclear magnetic resonance (NMR) measures of total HDL-particle (HDL-P), large HDL-
particle, and small and medium-sized HDL-particle (MS-HDL-P) concentrations and average
HDL-particle size with coronary artery calcification (CAC), which reflects the burden of …
