Background: The disturbances leading to cancer cachexia remain to be unraveled.
Preliminary evidence suggests that arginine availability in cancer is reduced. However, no
valid data are available on plasma arginine concentrations in cancer patients. Objective: We
aimed to determine whether there is evidence for disturbed arginine metabolism in cancer.
Design: We measured plasma arginine concentrations postabsorptively in patients with
various types of tumors, hypothesizing that arginine concentrations would be lower than …