Adenosine Potentiates Mediator Release from Human Lung Mast Cells1-4

PT Peachell, M COWMBO, A Kagey-Sobotka… - Am Rev Respir …, 1988 - atsjournals.org
PT Peachell, M COWMBO, A Kagey-Sobotka, LM Lichtenstein, G Marone
Am Rev Respir Dis, 1988atsjournals.org
Mlcromolar concentrations of adenosine were found to potentiate the release of hlsta· mine
and leulcotrleneC.(LTC.) from immunologically activated human lung mast cells (HLMC).
Structurally modified congeners of adenosine InclUding 5'-N-ethylcarboxamldeadenoslne
(NECA) and
Summary
Mlcromolar concentrations of adenosine were found to potentiate the release of hlsta· mine and leulcotrleneC.(LTC.) from immunologically activated human lung mast cells (HLMC). Structurally modified congeners of adenosine InclUding 5'-N-ethylcarboxamldeadenoslne (NECA) and
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