Recent literature suggests that the layer of adipocytes embedded in the skin below the
dermis is far from being an inert spacer material. Instead, this layer of dermal white adipose
tissue (dWAT) is a regulated lipid layer that comprises a crucial environmental defense.
Among all the classes of biological molecules, lipids have the lowest thermal conductance
and highest insulation potential. This property can be exploited by mammals to reduce heat
loss, suppress brown adipose tissue activation, reduce the activation of thermogenic …