BACKGROUND: Eosinophilic esophagitis (EE) is an emerging disorder with poorly
understood pathogenesis. OBJECTIVE: Whereas prior studies have primarily focused on the
role of eosinophils in disease diagnosis and pathogenesis, this study investigates the
involvement of mast cells. METHODS: Total and degranulated mast cell counts were
correlated to microarray and RT-PCR data to generate transcriptome expression profiles
related to mast cell number and degranulation in patients with EE and healthy control …