Viral reactivations and associated outcomes in the context of immune reconstitution after pediatric hematopoietic cell transplantation
R Admiraal, CCH de Koning, CA Lindemans… - Journal of Allergy and …, 2017 - Elsevier
Background Viral reactivations (VRs) after hematopoietic cell transplantation (HCT)
contribute to significant morbidity and mortality. Timely immune reconstitution (IR) is
suggested to prevent VR. Objectives We studied the relation between IR (as a continuous
predictor over time) and VR (as a time-varying predictor) and the relation between VR and
other clinical outcomes. Methods In this retrospective analysis all patients receiving a first
HCT between January 2004 and September 2014 were included. IR (CD3/CD4/CD8 T …
contribute to significant morbidity and mortality. Timely immune reconstitution (IR) is
suggested to prevent VR. Objectives We studied the relation between IR (as a continuous
predictor over time) and VR (as a time-varying predictor) and the relation between VR and
other clinical outcomes. Methods In this retrospective analysis all patients receiving a first
HCT between January 2004 and September 2014 were included. IR (CD3/CD4/CD8 T …
