Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA)
To the Editor: Vitiligo and alopecia areata (AA) share a similar pathogenesis, as they are
both interferon (IFN)-driven and dependent on CD8+ T cells. 1, 2 Here we report a case of
rapid, but not durable, repigmentation and hair regrowth in a 35-year-old man with
concurrent vitiligo and AA during treatment with oral ruxolitinib. His AA started at the age of
16 years as patchy hair loss on his arms, trunk, and scalp. Several years later, he reported
macular depigmentation on his face, trunk, and extremities, and notable overlap with …
both interferon (IFN)-driven and dependent on CD8+ T cells. 1, 2 Here we report a case of
rapid, but not durable, repigmentation and hair regrowth in a 35-year-old man with
concurrent vitiligo and AA during treatment with oral ruxolitinib. His AA started at the age of
16 years as patchy hair loss on his arms, trunk, and scalp. Several years later, he reported
macular depigmentation on his face, trunk, and extremities, and notable overlap with …