[HTML][HTML] MPC1-like is a placental mammal-specific mitochondrial pyruvate carrier subunit expressed in postmeiotic male germ cells
B Vanderperre, K Cermakova, J Escoffier… - Journal of Biological …, 2016 - ASBMB
Selective transport of pyruvate across the inner mitochondrial membrane by the
mitochondrial pyruvate carrier (MPC) is a fundamental step that couples cytosolic and
mitochondrial metabolism. The recent molecular identification of the MPC complex has
revealed two interacting subunits, MPC1 and MPC2. Although in yeast, an additional
subunit, MPC3, can functionally replace MPC2, no alternative MPC subunits have been
described in higher eukaryotes. Here, we report for the first time the existence of a novel …
mitochondrial pyruvate carrier (MPC) is a fundamental step that couples cytosolic and
mitochondrial metabolism. The recent molecular identification of the MPC complex has
revealed two interacting subunits, MPC1 and MPC2. Although in yeast, an additional
subunit, MPC3, can functionally replace MPC2, no alternative MPC subunits have been
described in higher eukaryotes. Here, we report for the first time the existence of a novel …
