Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized controlled trials
KR McQuaid, L Laine - The American journal of medicine, 2006 - Elsevier
PURPOSE: We performed a systematic review to define the relative and absolute risk of
clinically relevant adverse events with the antiplatelet agents, aspirin and clopidogrel.
MATERIALS AND METHODS: Databases were searched for randomized controlled trials of
low-dose aspirin (75-325 mg/dayay) or clopidogrel administered for cardiovascular
prophylaxis. Relative risks (RR) were determined by meta-analysis of 22 trials for aspirin
versus placebo and from single studies for aspirin versus clopidogrel, aspirin versus …
clinically relevant adverse events with the antiplatelet agents, aspirin and clopidogrel.
MATERIALS AND METHODS: Databases were searched for randomized controlled trials of
low-dose aspirin (75-325 mg/dayay) or clopidogrel administered for cardiovascular
prophylaxis. Relative risks (RR) were determined by meta-analysis of 22 trials for aspirin
versus placebo and from single studies for aspirin versus clopidogrel, aspirin versus …