Importance Oncolytic viruses (OVs) are emerging as important agents in cancer treatment.
Oncolytic viruses offer the attractive therapeutic combination of tumor-specific cell lysis
together with immune stimulation, therefore acting as potential in situ tumor vaccines.
Moreover, OVs can be engineered for optimization of tumor selectivity and enhanced
immune stimulation and can be readily combined with other agents. The effectiveness of
OVs has been demonstrated in many preclinical studies and recently in humans, with US …