[HTML][HTML] Osteoclasts and CD8 T cells form a negative feedback loop that contributes to homeostasis of both the skeletal and immune systems

ZS Buchwald, R Aurora - Journal of Immunology Research, 2013 - hindawi.com
Journal of Immunology Research, 2013hindawi.com
There are a number of dynamic regulatory loops that maintain homeostasis of the immune
and skeletal systems. In this review, we highlight a number of these regulatory interactions
that contribute to maintaining homeostasis. In addition, we review data on a negative
regulatory feedback loop between osteoclasts and CD8 T cells that contributes to
homeostasis of both the skeletal and immune systems.
There are a number of dynamic regulatory loops that maintain homeostasis of the immune and skeletal systems. In this review, we highlight a number of these regulatory interactions that contribute to maintaining homeostasis. In addition, we review data on a negative regulatory feedback loop between osteoclasts and CD8 T cells that contributes to homeostasis of both the skeletal and immune systems.
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