Differential aiolos expression in human hematopoietic subpopulations

K Billot, C Parizot, I Arrouss, D Mazier, P Debre… - Leukemia research, 2010 - Elsevier
The Aiolos transcription factor plays a crucial role in the control of lymphocyte differentiation
and proliferation. The expression of Aiolos isoform has been studied in lymphoid
pathologies but nothing is known about its expression in unaffected human hematopoietic
subpopulations. In this manuscript we show for the first time the differential Aiolos
expression at the RNA and protein level in hematopoietic cell subpopulations. B cells
express higher levels of Aiolos than NK and T cells while monocytes express almost …