Growth hormone and sex steroid administration in healthy aged women and men: a randomized controlled trial

MR Blackman, JD Sorkin, T Münzer, MF Bellantoni… - Jama, 2002 - jamanetwork.com
ContextHormone administration to elderly individuals can increase lean body mass (LBM)
and decrease fat, but interactive effects of growth hormone (GH) and sex steroids and their
influence on strength and endurance are unknown. ObjectiveTo evaluate the effects of
recombinant human GH and/or sex steroids on body composition, strength, endurance, and
adverse outcomes in aged persons. Design, Setting, and ParticipantsA 26-week
randomized, double-blind, placebo-controlled parallel-group trial in healthy, ambulatory …