It has been proposed that the presence of tubal intraepithelial carcinoma (TIC), in
association with one-third to nearly half of pelvic serous carcinomas, is evidence of fallopian
tube origin for high-grade serous carcinomas that would have been otherwise classified as
primary ovarian or peritoneal. To address this hypothesis, we evaluated a series of 114
consecutive pelvic (nonuterine) gynecologic carcinomas at our institution (2006 to 2008) to
determine the frequency of TIC in 52 cases in which all the resected fallopian tube tissue …