Asthmatic airway remodeling is the pathophysiological modifications of the normal airway
wall structure which include changes in the composition and organization of its cellular and
molecular constituents. These modifications are the major cause of the symptoms
associated with decreased pulmonary function. Airway remodeling is partially reversible in
mild asthma but mostly irreversible in chronic severe asthma. It is initiated as a repair
process in response to airway wall injuries caused by inflammation; however, dysregulation …